Anxiety and depression are pathologies that affect human beings in many aspects of life, including social life, productivity and health. Cannabidiol (CBD) is a constituent non-psychotomimetic of Cannabis sativa with great psychiatric potential, including uses as an antidepressant-like and anxiolytic-like compound. The aim of this study is to review studies of animal models using CBD as an anxiolytic-like and antidepressant-like compound. Studies involving animal models, performing a variety of experiments on the above-mentioned disorders, such as the forced swimming test (FST), elevated plus maze (EPM) and Vogel conflict test (VCT), suggest that CBD exhibited an anti-anxiety and antidepressant effects in animal models discussed. Experiments with CBD demonstrated non-activation of neuroreceptors CB1 and CB2. Most of the studies demonstrated a good interaction between CBD and the 5-HT1A neuro-receptor.
You can develop a tolerance to cannabis if you use it regularly. This means you need more to get the same effect.
Cannabis will go into your bloodstream when smoked. It will quickly be carried to your brain and stick to your receptors. This will affect your mood and behaviour.
Can cannabis affect my mental health?
You might have lower motivation. And cannabis can affect how you sense things. You may see, hear or feel things differently. This is known as hallucinating. Hallucinations can be a sign of psychosis.
Telephone admin: 020 3817 9410
Address: 2nd Floor, 120 Cromer Street, London, WC1H 8BS
Email: [email protected]
People use cannabis for different reasons. Sometimes they use it to relieve mental or physical symptoms. This is called self-medication. This may make you feel better in the short term. But in the longer term it can increase problems or create new ones.