Cannabidiol and THC are just two of the plant’s more than 100 cannabinoids. THC is psychoactive, and CBD may or may not be, which is a matter of debate. THC can increase anxiety; it is not clear what effect CBD is having, if any, in reducing it. THC can lead to addiction and cravings; CBD is being studied to help those in recovery.
What are the claims?
Recently, the F.D.A. sent a warning letter to Curaleaf Inc. about its “unsubstantiated claims” that the plant extract treats a variety of conditions from pet anxiety and depression to cancer and opioid withdrawal. (In a statement, the company said that some of the products in question had been discontinued and that it was working with the F.D.A.)
Does CBD help sleep and depression?
But without clinical trials in humans, psychologists say CBD’s effect on depression is still a hypothesis, and not an evidence-based treatment.
Approved to Treat Epilepsy
Most of these studies have focused on animal participants, and further research is needed. Experts recommend awareness around these potential side effects when prescribing cannabis to patients who are of reproductive age.
Amounts and Dosage
Though not much research has looked specifically at CBD, it seems that there is a negative relationship between cannabis use and sperm count, as well as other measures of male fertility, including sperm viability and motility.