CBD Gummies For Dementia Patients


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Pure Craft CBD offers CBD Oil 1000mg & 2000mg flavored CBD tinctures, CBD Gummy Bears, CBD Oil for Dogs and more! Discover Pure Craft CBD PURE CRAFT BLOG Cannabis will be used to treat dementia patients in the first major trial in the U.K. Can CBD oil help with dementia symptoms and its downstream side effects? Can a Daily Dose of CBD Help With Dementia? The World Health Organization states that no treatment has been found to cure dementia completely.

Can CBD Help With Alzheimer’s & Dementia?

With no known cure and challenges in managing symptoms, patients and families are desperate for anything that might help. So it’s not surprising that CBD has found itself among the long list of potential treatments being explored for Alzheimer’s and dementia.

Can CBD do anything for people with dementia? Here’s what we know so far.

Dementia Defined

Dementia is the umbrella term for a set of symptoms dealing with a decline in cognitive function. This can include memory loss, difficulties with engaging in daily tasks, and changes in communication.

It primarily impacts older adults, though it isn’t a normal part of aging.

Dementia is quite common, with an estimated 5 million adults in the United States living with the condition.(2)

Dementia Symptoms

The symptoms of dementia generally cluster around cognitive and communication problems and challenges. And, symptoms usually worsen over time.

Common symptoms include issues with:(2)

  • Attention
  • Memory
  • Communication
  • Judgment

While it’s normal to have age-related memory changes, dementia patients tend to have more serious memory loss issues. For instance, they may forget how to get home or the name of a close family member.

Dementia Risk Factors

It’s thought that dementia is caused by damage or loss of the brain’s nerve cells. Exactly why this happens isn’t clear, but the following things increase your chances of getting dementia:(2)

  • Age
  • Cardiovascular issues
  • Traumatic brain injury
  • Family history of dementia
  • Race/ethnicity (African Americans are 2x more likely to develop dementia than white Americans.)

Alzheimer’s Disease

Alzheimer’s disease is the most common type of dementia, with about 60-80% of dementia cases attributed to Alzheimer’s.(2) Alzheimer’s is a progressive disease, meaning that it gets worse over time.

The buildup of beta-amyloid plaques and neurofibrillary tangles in the brain are thought to contribute to the development of Alzheimer’s. Chronic inflammation in the brain is also suspected of advancing the disease.(3)

Dementia Treatment

There’s unfortunately no cure for dementia, but different treatments exist to help ease symptoms, manage the disease, and improve quality of life. There’s a huge need for research into this area of neurodegenerative diseases so new, effective treatments can be discovered.

Dementia Prevention

Prevention is not guaranteed — but living a healthy lifestyle can lower your risk. Some of the things that can lower your risk of developing dementia include:(4)

  • Keeping the brain engaged through puzzles, word games, and reading
  • Regular exercise
  • Getting enough vitamins, especially vitamin D
  • Keeping a healthy diet
  • Managing any cardiovascular issues
  • Getting enough sleep

The Endocannabinoid System & Dementia

Neurodegenerative diseases like Huntington’s disease, Parkinson’s disease, vascular dementia, and Alzheimer’s are associated with the endocannabinoid system.(5) And studies on Alzheimer’s patients are finding changes in the way the endocannabinoid system (ECS) functions.(6)

The body can produce its own cannabinoids. These endocannabinoids help the body regulate many different functions. At the same time, phytocannabinoids like CBD can also interact with the body’s ECS. And cannabinoids like CBD have shown that they may have neuroprotective properties.(7)

This may be why scientists are investigating whether CBD could help to treat Alzheimer’s and dementia.

Lab Research On Alzheimer’s

One 2016 study found that cannabis compounds, particularly THC, facilitated the removal of beta-amyloid — the protein that forms plaques in Alzheimer’s patients’ brains.(8)

Studies like these suggest that cannabinoids may have neuroprotective properties that might reduce inflammation and beta-amyloid accumulation.

This particular study was done in lab-grown neuron cells, so naturally, more research is needed to know how the results would translate into human patients.

Cannabis & Alzheimer’s

Other studies have looked at how cannabinoids can affect Alzheimer’s patients’ quality of life. One study on patients with moderate to severe Alzheimer’s disease found that nabilone (synthetic medical form of THC) helped significantly reduce agitation and improved overall behavioral symptoms.(9)

Others have looked into cannabis as a whole, with some experts suggesting that CBD with THC may be more beneficial than just using CBD or THC alone.(10)

CBD For Alzheimer’s & Dementia

In 2020, a randomized clinical trial began to investigate CBD’s effectiveness in reducing agitation in patients with Alzheimer’s and other forms of dementia.(11) Study participants are either given a CBD oil (containing no THC) or a placebo.

The hemp-derived CBD capsules are being given for 6 weeks. The dose is set to 15mg twice a day, and will go up to 45mg twice a day.

The study aims to measure seven outcomes:

  • Changes in agitation and aggression
  • Change in caregiver burden
  • Change in patient’s quality of life
  • Change in caregiver’s quality of life
  • Changes in cognitive skills
  • Impact to sleep
  • Changes to neuropsychiatric symptoms

If the study shows promising results, it could pave the way for more research on CBD as a treatment for Alzheimer’s and other forms of dementia.

The study is estimated to be completed in February 2023. Stay tuned!

Tips In Incorporating CBD Into Your Wellness Plan

CBD doesn’t yet have an approved use in the treatment of dementia. But some research shows that it might help ease the aggression that comes with Alzheimer’s disease. It may also offer some other benefits like easing stress and chronic pain.

If you want to access the potential plant benefits of this cannabinoid, follow these guidelines:

  • Consult with your medical team first. CBD may interact with various medications so be sure to get the OK from the doc.
  • Find a quality CBD retailer. Look for organic hemp-derived products, with high bioavailability for the best absorption.
  • Find your best form of CBD. This could be isolate CBD, broad-spectrum CBD, or full-spectrum CBD. Read our guide Different Types of CBD: Full-Spectrum, Broad-Spectrum & Isolate to learn more.
  • Choose a CBD product that works with your wellness routine.CBD oil, CBD softgels, and CBD gummies are all viable options. For more guidance, check out Which CBD Product is Right For You: CBD Tinctures, Gummies, Topicals & Softgels.

CBD & Dementia: The Bottom Line

There’s no evidence yet that CBD can prevent or reverse Alzheimer’s and other dementias. But it might help alleviate some of the unpleasant symptoms that accompany it.

Most research on CBD and dementia has found that CBD and cannabis may reduce irritability and aggression among dementia and Alzheimer’s patients. Research has also found neuroprotective qualities in cannabidiol, so this bodes well for future investigations into the compound.

For anyone considering CBD, know that it’s no replacement for traditional medications — but it could be a complementary wellness tool to help you boost overall well-being.

CBD Oil for Alzheimer’s & Dementia: How to Use & Dosage

Hemp and CBD oil were federally legalized with the 2018 Farm Bill, but scientists have been researching cannabidiol and its potential benefits for many years prior to the cannabis boom.

CBD products are gaining popularity at a rapid pace, mainly due to the number of conditions potentially alleviated by this compound.

Researchers are discovering new symptoms that CBD may be able to treat or help with in some way — from anxiety to inflammation and neurodegenerative diseases like dementia. CBD may provide relief to thousands of people across the country.

In this article, I’ll dive specifically into the potential application of CBD for dementia and the collateral damage it does to individuals suffering from this disease.

I want to explain the ins and outs of using CBD oil, how it can interact with dementia, and guide you through the brands that currently offer the best CBD products on the market.

Best CBD Oils for Dementia

Not all CBD is made equal. In fact, there’s a large degree of difference when it comes to the quality of ingredients in different CBD oils.

If you’re using this supplement for dementia, it’s important to find something clean and as high quality as possible — preferably in a higher potency.

Here are my top 4 recommended products that meet those requirements:

1. Royal CBD

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  • Royal CBD uses organic hemp from local farmers
  • The company makes its products with supercritical CO2 extraction
  • Available as full-spectrum CBD and isolate
  • Four potency strengths to choose from: 250mg, 500mg, 1000mg, and 2500mg
  • The oil is potent — it contains up to 83.3 mg of CBD in each mL
  • Suspended in premium MCT oil for better taste and improved absorption
  • Every batch of product has been tested for potency and purity in a 3rd-party laboratory
  • The 2500 mg oil is available only in the unflavored option
  • Royal CBD products are slightly more expensive than the competition given the quality of ingredients this company uses
My Thoughts on Royal CBD:

Royal CBD is a rising star of premium CBD oils — offering high-quality products made from organically-grown American hemp. The oil contains the full spectrum of cannabinoids and terpenes, providing the synergy from these compounds and contributing to the higher efficacy of CBD.

Aside from extracting its oil with pressurized CO2, Royal CBD sends each batch of products to independent laboratories for testing. This is used to confirm the potency and purity of every bottle sold.

The oil offers 250 mg to 2500 mg of full-spectrum CBD per bottle, suiting both novice consumers and experienced users or those with more severe symptoms.

I like how this product tastes. Because it’s suspended in high-quality MCT oil, it doesn’t leave that bitter, earthy aftertaste on the tongue. The flavor is masked by nutty rather than earthy notes.

But if you prefer other forms of administration, Royal CBD offers convenient soft gel capsules (25 mg of CBD per piece) and isolate-based gummies (10 mg of CBD per count). These forms may not have the fastest onset but are easier to dose and take on the go.

2. Gold Bee

  • Unique product selection
  • Gold Bee uses non-GMO, Colorado-grown hemp
  • The oil contains full-spectrum CBD
  • The company’s products are extracted with CO2
  • You’re getting up to 2400 mg of CBD per bottle
  • The oil is sweetened with organic honey
  • Third-party lab tested for potency and purity
  • No low-strength oils
  • Not available in-store
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My Thoughts On Gold Bee:

This company is a true individual among other CBD brands. For Gold Bee, honey is the name of the game. Coming from the superfoods industry, Gold Bee’s founders have decided to combine two ancient therapeutic ingredients: cannabinoids from organic hemp and honey sourced in Brazillian rainforests. Gold Bee offers full-spectrum CBD oil (sweetened with honey), high-potency capsules, gummies, and delicious honey sticks. All products are non-GMO, vegan, and 3rd-party tested for potency and purity.

The Gold Bee CBD oil comes in two concentrations, packing 1200 mg or 2400 mg of CBD per bottle. A single serving of this oil contains 40 mg of full-spectrum CBD for the 1200 mg bottle. This means you’re getting the synergistic effects provided by cannabinoids, terpenes, and other natural compounds found in hemp. Surprisingly for a whole-plant extract, this product has a subtle flavor thanks to the infusion in MCT oil. As a result, the oil is also more available for the body to process. There are also two flavored versions available (kiwi, and lychee); it contains natural flavorings and is sweetened with honey, doing a great job at masking the earthy taste of natural CBD oil.

For me, this product is definitely a go-to mood booster and anxiety reliever. While it’s not the most potent CBD oil out there, it can easily compete with stronger products that are often priced higher.

3. CBDPure

  • CBDPure’s products are sourced from organic hemp grown in Colorado
  • The company uses CO2 extraction in all their products
  • The oil is sold in larger bottles than the competition (60 mL)
  • These products are made with full-spectrum hemp extract
  • The entire product lineup has been tested in an independent laboratory for quality assurance
  • Narrow product range
  • The oil is less potent than Royal CBD
  • No isolates available
My Thoughts on CBDPure:

If you don’t know where to start and need plenty of information about each stage of the CBD oil manufacturing stage, CBDPure is one of the best brands you can choose. This company is very transparent and uses organic hemp in every product they offer.

Similar to Royal CBD, CBDPure prefers to keep things simple, offering two types of products — oil drops and capsules.

Their CBD oil comes in 60 mL bottles but is slightly less potent than Royal CBD, so you may choose this option if you benefit from lower doses, which isn’t common for people with dementia symptoms.

If you want a product that will give you more CBD and offer consistent dosing, you may go for CBDPure softgels. Each capsule comes with 25 mg of full-spectrum cannabidiol.

4. CBDistillery

  • CBDistillery uses Colorado-grown hemp
  • The company’s products are available as ‘full-spectrum’ or ‘pure oil’ (zero THC)
  • Broad product selection
  • The oil is very potent — up to 5,000 mg of CBD per bottle
  • CBDistillery sends samples of their CBD oil to a third-party laboratory for thorough content analysis
  • It’s one of the most affordable brands on the market
  • Their hemp isn’t organic
  • The CBD oil is available only in the unflavored version
My Thoughts on CBDistillery:

CBDistillery is a Colorado-based brand with a diverse product selection. Out of all their products, my favorite is their full-spectrum CBD oil. Interestingly, this product is also available as pure oil, with no THC inside.

The oil comes in a wide potency range, from 250 to 5,000 mg of total CBD. The company caters to different types of CBD consumers and budgets.

Their oil may not be as high quality as Royal CBD or CBDPure — it’s not made from organic hemp — but this is well justified by the cost of their products. CBDistillery doesn’t sell the best CBD oil out there, but that’s definitely the best CBD oil in this price range.

On top of making affordable CBD products, CBDistillery is known for its influence on raising awareness about the health benefits of cannabis. They have created the #CBDMOVEMENT hashtag to provide education for customers in their social media.

What is Dementia?

Dementia is not a disease, per se. Instead, it’s a group of conditions that impair the functioning of your brain.

Generally, dementia is characterized by the deterioration of at least two important brain functions, such as weakened judgment and memory loss. As a matter of fact, any form of dementia can compromise cognitive functioning.

As with every health condition, there are certain symptoms that can help diagnose dementia, namely:

  • Impairment of motor functions and coordination
  • Memory loss usually noticed first by a close family member
  • Personality changes
  • Difficulty with problem-solving or reasoning
  • Anxiety, agitation, depression, or paranoia
  • Confusion
  • Hallucinations and awkward behavior
  • Problems handling complex tasks

Is Dementia the Same as Alzheimer’s Disease?

Alzheimer’s is the most common form of dementia, so dementia is just a category that Alzheimer’s Disease belongs to. Yet, there are other forms of dementia besides Alzheimer’s.

Dementia can be categorized into four different forms of dementia:

  1. Frontotemporal dementia: the type where the nerve cells in the temporal and frontal lobes of the brain degenerate. Frontotemporal dementia affects the parts of the brain that control behavior, language, and personality
  2. Lewy Body Dementia: the most common type of progressive dementia, Lewy Body Dementia occurs when abnormal clumps of protein start to form in the brain.
  3. Vascular Dementia: it’s the second most prevalent form of dementia. It’s caused by the damage in the blood vessels that limits direct blood supply to the brain and may lead to blood vessel clogs or stroke.
  4. Mixed dementia: it typically involves some combination of Alzheimer’s Disease and other forms of dementia. While Alzheimer’s may strike those over the age of 65, mixed dementia occurs upon further progression.

What Are the Benefits of CBD for Dementia?

CBD has been proposed by scientists as a natural alternative for many serious conditions including memory loss conditions, anxieties, and sleep disorders.

CBD is a potent antioxidant, anti-inflammatory, and neuroprotectant, so it may greatly improve brain functioning, which is essential in slowing and halting the progression of neurodegenerative diseases.

Below I explain how CBD oil could improve different forms of dementia based on the latest scientific findings.

1. Alzheimer’s Disease

Research shows a clear link between CBD and the reduction of inflammation and brain cell decline.

Inflammation increases the negative impact of Alzheimer’s disease. It’s a core cause of this condition. The more inflamed the brain, the greater the damage.

Alzheimer’s sufferers often show a path of rapid decline and degeneration of brain cells in certain regions. Scientists have recently found that CBD has the potential of improving the plasticity of the hippocampal region — the part of the brain responsible for cognitive functioning and forming memories.

In clinical trials, researchers have found that the endocannabinoid system is involved in neurotransmission, neuropathology, and neurobiology of different forms of dementia, including Alzheimer’s Disease.

2. Vascular Dementia

As mentioned, people who have vascular dementia typically encounter problems with planning, reasoning, memory, judgment, and other thought processes due to brain damage from reduced blood flow to their brains.

A 2016 study conducted by the National Institute of Health (NIH) found that activating cannabinoid receptors in the brain promoted the recovery of blood flow to the brain.

3. Parkinson’s Disease Dementia

Parkinson’s is a progressive neurodegenerative disease mainly affecting middle-aged and elderly people. Some symptoms of dementia may be the result of Parkinson’s disease — referred to as Parkinson’s disease dementia.

Scientists suggest that Parkinson’s disease may derive from lowered dopamine production and is most commonly expressed by muscular strains, tremors, and slow, flawed movement.

A digestive imbalance may also be a significant factor in the progression of Parkinson’s and the seriousness of its symptoms. Cannabinoids such as CBD have been shown to produce neuroprotective and antioxidant effects on the brain which, along with its anti-inflammatory properties, can be effective in managing Parkinson’s disease-induced dementia.

4. Lewy Bodies Dementia

Lewy Bodies is a scientific name for the alpha-synuclein protein deposits in the brain. These buildups can lead to problems with judgment, sleeping, behavior, movement, and mood.

Research has found that CBD may reduce anxiety and stabilize mood. In addition, the anti-inflammatory effects of CBD can reduce the severity of motor symptoms and help with sleep regulation.

5. Frontotemporal Dementia

As the brain loses more cells in its frontal or temporal lobes, this can trigger symptoms of depression and psychosis. Unlike many antipsychotic drugs, CBD may alleviate tremors, anxiety, and rigidity without the side effects associated with prescription drugs.

6. Huntington’s Disease Dementia

Also known as Huntington’s chorea, this disease is an inherited disorder that leads to degeneration of brain cells — which often results in symptoms of dementia.

The earliest symptoms of this condition are often mild and involve problems with mood and concentration. As the disease progresses, a person may suffer from a general lack of coordination and an unsteady gait (walking motion).

A 2016 study conducted by researchers from the University of Madrid discovered that CBD’s antioxidant and anti-inflammatory properties can be beneficial for managing Huntington’s disease and is safe even at very high doses.

What Experts Say About CBD Oil and Dementia

Scientists are going to use a CBD/THC oral spray Sativex to treat dementia patients in the first major trial in the UK. The study is led by researchers at King’s College London and funded by Alzheimer’s Research UK.

Researchers will be investigating the efficacy of Sativex, a drug already approved for patients with multiple sclerosis, by observing 60 patients between the age of 55–90 who are living in care homes for the duration of the trial. The study will aim at easing aggression and agitation, one of the main symptoms of dementia.

Dag Aarsland, a psychiatrist and the professor supervising the trial says:

“Most often, people associate Alzheimer’s disease with memory problems, but this is just one aspect of a complex condition that can affect people in different ways. Many people with Alzheimer’s can become agitated or aggressive, and this can pose difficulties for the person with the condition and those closest to them.”

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If full-spectrum extracts prove effective as a dementia treatment, this can be a breakthrough for modern medicine considering that scientists have been struggling to come up with effective solutions for almost two decades.

“With no new dementia treatments in over 15 years, it is vital that we test a wide range of approaches to find effective ways to help people living with the condition,” said David Reynolds, Ph.D., of Alzheimer’s Research U.K. Reynolds underlines the importance of finding a medicine that will not only slow or stop the progression of dementia but also benefits people’s day-to-day performance.

“Based on some preliminary studies in other populations, like younger individuals with bipolar disorder and schizophrenia, as well as animal studies, there is at least some reason to theorize these drugs would have a benefit,” follows Dr. Nathan Herrmann, head of geriatric psychiatry department at Sunnybrook Health Sciences Centre in Canada, showing support for his colleagues in the UK.

Sativex has equal amounts of THC and CBD. Hemp-derived CBD oil contains only 0.3% THC and there are no trials that would look into the effects of this cannabis solution on dementia.

What’s the Best CBD Oil Dosage for Dementia?

There are no definite dosage guidelines when it comes to using CBD oil for dementia. However, various studies have been performed on the efficacy of different CBD doses for Alzheimer’s patients.

A study conducted in 2014 found that higher concentrations of CBD may be required until the effects take hold. The study was conducted on transgenic mice.

Given the lack of regulation in the CBD marketplace, the best thing you can do is observe the effects of different dosages and report to a foundation or science institute that specializes in seeking new forms of dementia treatment. With more self-reports from patients, healthcare professionals will be able to come up with some general guidelines for people with dementia in the future.

Where to Buy CBD Oil for Dementia

If you’ve been considering taking hemp-derived CBD oil for dementia, you can buy one in a local cannabis dispensary or search for CBD products online.

I prefer buying CBD oil online. The majority of CBD supplements are sold this way, so you get access to a wider range of products. Cannabis dispensaries have plenty of CBD supplements as well, but they may not carry the best products out there, not to mention that they might have stood on the shelves for a long time after arrival — which is not the best way to store CBD oil.

Buying CBD oil online is also more convenient. You can easily check the reputation of your potential supplier. Always make sure that your manufacturer uses organic hemp, makes its products with CO2 extraction, and posts testing results from 3rd-party laboratory screening.

Finally, online stores are less expensive than dispensaries. Usually, you will pay around twice as much for CBD oil in a local dispensary than you would for a product ordered online.

It’s worth waiting the extra 2-3 days to get exactly what you’ve been looking for without spending an arm and a leg.

Final Thoughts on Using CBD Oil for Dementia

Dementia is a severe neurodegenerative condition. It’s not a disease per se; instead, it’s a set of symptoms that describe a predictable set of symptoms. It can take many forms, from Alzheimer’s Disease to vascular dementia and Lewy Bodies Dementia. Dementia can also result from the progress of other neurodegenerative diseases, such as Parkinson’s or Huntington’s Disease.

Scientists have been investigating the neuroprotectant properties of CBD and its influence on neurodegeneration for quite some time now. While the evidence isn’t conclusive yet, results from animal studies and preclinical trials indicate that the endocannabinoid system and cannabinoids can be used to prevent neurodegeneration and reverse its impact with consistent administration.

If you’re interested in trying CBD oil for dementia, make sure to contact your doctor first to figure out whether CBD is good for you, especially if you’re already using some medication.

  1. Prenderville, J. A., Kelly, Á. M., & Downer, E. J. (2015). The Role of Cannabinoids in Adult Neurogenesis. British Journal of Pharmacology, 172(16), 3950–3963.
  2. Walther, S., & Halpern, M. (2010). Cannabinoids and Dementia: A Review of Clinical and Preclinical Data. Pharmaceuticals (Basel, Switzerland), 3(8), 2689–2708.
  3. Karl, T., Cheng, D., Garner, B., Arnold, J.C. (2012). The Therapeutic Potential of the Endocannabinoid System for Alzheimer’s Disease. Expert Opinion on Therapeutic Targets, 16(4), 407–420.
  4. Benyo, Z., Ruisanchez, E., Leszl-Ishiguro, M., Sandor, P., Pacher, P. (2016). Endocannabinoids in Cerebrovascular Regulation. American Journal of Physiology. Heart and Circulatory Physiology, 310(7), 785–801.
  5. Peres, F. F., Lima, A. C., Hallak, J., Crippa, J. A., Silva, R. H., & Abílio, V. C. (2018). Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?. Frontiers in pharmacology, 9, 482.
  6. Ibeas Bih, C., Chen, T., Nunn, A. V., Bazelot, M., Dallas, M., & Whalley, B. J. (2015). Molecular Targets of Cannabidiol in Neurological Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 12(4), 699–730.
  7. Maroon, J., & Bost, J. (2018). Review of the Neurological Benefits of Phytocannabinoids. Surgical Neurology International, 9, 91.
  8. Lopez-Sendon Moreno, J.L. et al. (2016). A Double-Blind, Randomized, Cross-Over, Placebo-Controlled, Pilot Trial With Sativex in Huntington’s Disease. Journal of Neurology, 263(7), 1390–1400.
  9. Cheng, D., Spiro, A.S., Jenner, A.M., Garner, B., Karl, T. (2014). Long-term Cannabidiol Treatment Prevents the Development of Social Recognition Memory Deficits in Alzheimer’s Disease Transgenic Mice. Journal of Alzheimer’s Disease, 42(4), 1383–1396.
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

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CBD for Dementia – August 2022

According to the World Health Organization, no treatment has been found to cure dementia completely (6 ) .

There are many types of dementia, namely Alzheimer’s, vascular dementia, Lewy body dementia, Huntington’s disease, Parkinson’s disease, and frontotemporal dementia (7 ) .

The treatment options available cannot stop dementia nor reverse its progression (8 ) . The approved treatments also have limited therapeutic effects and have been discovered to have adverse effects on dementia patients.

Medications used to treat Alzheimer’s, the most common form of dementia, can cause vomiting, nausea, diarrhea, weight loss, hallucinations, dizziness, and fatigue (9 ) .

For these reasons, family members of dementia patients are turning to cannabidiol (CBD), the active ingredient of the cannabis plant that does not generate a high in users.

Recent studies suggest that CBD may help in the treatment of dementia.

A study in 2019 that was published in the journal Therapeutic Advances in Drug Safety has shown that cannabinoids , like CBD , had promising therapeutic effects on dementia (10 ) . The study reported that the use of CBD on dementia patients was proven to be safe.

Another study was conducted on ten female dementia patients that had severe behavior problems.

Researchers concluded that higher dosages of a combination of CBD and tetrahydrocannabinol (THC) improved the test subjects’ behavior problems (11 ) . THC is the active ingredient of Cannabis Sativa that can generate a high in users.

Muscle rigidity also markedly improved, thereby making transfers and daily care easier for staff handling dementia patients.

In the 2019 study, the researchers gradually increased the dosage of the THC and CBD combination, hence exhibiting positive results.

How CBD Oil Works to Alleviate Symptoms of Dementia

CBD’s potential benefits to manage dementia include its ability to reduce inflammation. It also might help stimulate the brain and protect the nervous system (12 ) .

CBD may also attenuate anxiety and stress and reduce the decline of cognitive functions , such as memory.

According to a 2017 study, CBD demonstrates anti-inflammatory and antioxidant properties. It also acts as a neuroprotectant that improves brain functions (13 ) .

The study focused on Alzheimer’s and discovered that CBD is anti-inflammatory, as it reduced critical elements in reactive gliosis, namely inducible nitric oxide synthase (iNOS) and glial fibrillary acidic protein (GFAP).

In gliosis, glial cells undergo a reactive change caused by damage to the central nervous system (CNS).

Glial cells are the most abundant cells in the CNS. They surround, support, and provide insulation between neurons (14 ) .

Another study conducted on Alzheimer’s patients outlined CBD’s ability to prevent the production of amyloid-beta proteins (15 ) , which are large membrane proteins essential for neural growth and repair.

In later life, these proteins collect in the brain cells, destroy synapses, and clump into plaques that eventually result in nerve cell death (16 ) , leading to the loss of thought and memory.

The researchers also concluded that CBD helps in the suppression of gene production related to Alzheimer’s disease.

CBD as Anti-Inflammatory

A 2018 study said that CBD reduced neuroinflammation (17 ) . The study also demonstrated CBD’s ability to decrease inflammatory cytokine production.

Cytokines are molecules that help in cell-to-cell communication in immune responses. They are also responsible for the movement of cells towards infection, trauma, and inflammation sites in the body (18 ).

CBD as Antioxidant

Oxidative stress occurs when oxidants outnumber antioxidants (19 ) .

Oxidative stress is a major cause of neurodegenerative diseases, specifically Alzheimer’s and vascular dementia (20 ) . It is also involved in other diseases like Parkinson’s and Huntington’s.

A study on mice reveals that CBD has antioxidant properties. It also has anti-inflammatory and neuroprotective effects (21 ) .

CBD as Brain Stimulant, Neuroprotectant

CBD may have therapeutic benefits to the nervous system and its brain cells.

According to a study done in 2017 and published in the journal Frontiers in Pharmacology , CBD promotes hippocampal neurogenesis (22 ) . This occurrence is the production of new neurons in the hippocampus.

Hippocampal neurogenesis significantly decreases in patients with Alzheimer’s (23 ) .

A study on the treatment of Alzheimer’s reveals that long-term use of cannabidiol helps prevent the development of social recognition memory impairments in rodents (24 ) . The study highlights CBD’s antioxidant, neuroprotective, and anti-inflammatory properties.

Researchers revealed that CBD’s neuroprotective properties are related to its ability to reduce inflammation and oxidative stress. It also helps modulate glial cells and helps prevent the death of nerve cells (25 ) .

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The study also discovered that CBD had neuroprotective effects and therapeutic benefits for patients with Parkinson’s disease.

Another study that was also done on Parkinson’s disease patients showed CBD’s efficacy in treating psychosis that comes with the disease (26 ) . For four weeks, the test subjects were given a flexible dose of CBD, starting with an oral dose of 150 mg per day.

The researchers concluded that CBD might be useful in treating psychosis in Parkinson’s disease patients. The test subjects did not experience adverse side effects during the clinical trial.

CBD for Nightmares

A study has found that CBD helps improve sleep-related conditions that are associated with rapid eye movement sleep behavior disorder in patients who have Parkinson’s disease (27 ) . Some of these conditions include paralysis of muscles during nightmares and active behavior when one is dreaming.

The Pros and Cons of CBD Oil for Dementia

The Pros
  • Studies conducted on humans and animals have revealed CBD’s therapeutic properties that may help treat the various conditions classified under dementia.
  • Medications for dementia have several side effects, including nausea, vomiting, diarrhea, and hallucinations, among others (28 ) . Meanwhile, CBD generally has an excellent safety profile as its side effects are minimal. The most common are diarrhea, tiredness, and changes in weight or appetite (29 ) .
  • The World Health Organization has not recorded any case of CBD dependence in humans (30 ) . Hence, it is not a substance that has the potential for abuse.
  • As long as state laws allow CBD use, buying CBD products does not require a prescription.
The Cons
  • There is a need for further research on medical cannabis-related products , like CBD , in the treatment of dementia and its many diseases.
  • There is a need for a standard dosage for CBD when used as a dementia treatment. Currently, the United States (US) Food and Drug Administration (FDA) has not approved its use for mental health-related conditions and other ailments except for epilepsy.
  • Cholinesterase inhibitors are typically prescribed for dementia treatment. Some of the commonly used cholinesterase inhibitors include donepezil and galantamine. These are both metabolized by cytochrome P450 (31 ) . Caution should be taken when using CBD with these dementia medications because of possible drug interactions. CBD may reduce the efficacy of these medications as it can inhibit these liver enzymes (32 ) .
  • There have been incidences of mislabeled CBD products because the FDA does not regulate these (33 ) . Buyers should be cautious and should only purchase from credible manufacturers.

How CBD Oil Compares to Alternative Treatments for Dementia

Dementia medications typically cause the following:

  • Nausea
  • Vomiting
  • Diarrhea
  • Appetite loss
  • Muscle pain
  • Sleep problems
  • Fatigue
  • Headaches
  • Itchiness or rashes
  • Dizziness
  • Hallucinations
  • Agitation or aggression

Because of these side effects, which can be especially detrimental to elderly dementia patients, people have been exploring alternative treatments.


One alternative dementia remedy is acupuncture. Compared to massage therapies that focus on the stimulation of movement and blood flow in the body, acupuncture is believed to enhance the flow of energy in the body (34 ) .

A study published in the journal Evidence-Based Complementary and Alternative Medicine states that acupuncture was more effective when used alongside Western medication and herbal medication (35 ) .

The researchers concluded that acupuncture had mixed efficacy in treating cognitive impairments and dementia.

Herbal Supplements

Herbal supplements are also used for the treatment of dementia. These herbal remedies include Ginkgo Biloba , as clinical studies have shown that it helps in memory loss (36 ) .

Reports state that a standard preparation of the herb improves neurocognition and enhances the everyday activities of Alzheimer’s and vascular dementia patients.


Compared to these remedies that only treat a few aspects of dementia, the use of cannabis-related products, like CBD, may have more advantages.

CBD’s antipsychotic and neuroprotective properties may help alleviate the various symptoms of dementia.

World Health Organization findings show that in the early stages of dementia, it is overlooked as its onset is gradual (37 ) .

Symptoms vary, but they are generally cognitive and psychological changes.

Mayo Clinic lists the following symptoms of dementia (38 ) :

Cognitive changes:

  • Memory loss
  • Difficulty communicating or finding words
  • Difficulty with spatial and visual abilities (getting lost while driving)
  • Difficulty solving problems or reasoning
  • Difficulty handling tasks that are complex
  • Planning and organizing difficulties
  • Coordination and motor function problems
  • Disorientation and confusion

Psychological changes:

CBD for Cognitive Functions

A study in 2018 has found that long-term medical use of CBD results in improved cognition, particularly in memory, verbal learning, and attentional switching (39 ) .

Another study conducted on schizophrenic patients has shown that CBD improves cognition in multiple impairment studies (40 ) . These preclinical models of cognitive impairment include Alzheimer’s, neuro-inflammatory, and neurological disorders.

CBD for Depression

A study in 2018 and published in the journal Frontiers in Immunology outlines CBD’s ability to alleviate the symptoms of depression, epilepsy, schizophrenia, social phobia, bipolar disorder, Parkinson’s disease, among others (41 ) .

The researchers concluded that CBD’s antipsychotic and anxiety-reducing effects help in the treatment of various conditions.

CBD for Anxiety

A study reports CBD’s anxiety-reducing effects and its potential in treating various types of anxiety, including social anxiety disorder, panic disorder, generalized anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (42 ) .

How To Choose The Right CBD for Dementia

Before purchasing a CBD oil product, it is essential to know its three types: full-spectrum CBD oil, broad-spectrum, and isolates.

In a full-spectrum CBD oil, all the parts of a cannabis plant are used. These are trace amounts of THC, terpenes, fatty acids, flavonoids, and essential oils. F

Full-spectrum CBD oil is believed to be the most effective type of CBD oil because all the ingredients of Cannabis Sativa synergize for maximum therapeutic effect, known as the entourage effect.

It is important to note that THC, however, may be detected via drug tests. It can also cause mild psychoactive effects. For those who want to avoid these risks, using broad-spectrum CBD is more recommended.

Broad-spectrum CBD oils have the same components as full-spectrum oils except for THC. People seeking to use CBD purely or avoiding its other components because of allergies may resort to using CBD isolates. These are made from isolated cannabidiol alone, so they are pure CBD.

There is a significant difference between CBD oil and hemp oil (also known as hemp seed oil or hemp extract). CBD is derived from a hemp plant’s flowers, stalks, and leaves. Meanwhile, hemp oil is extracted from raw hemp seeds. Because of this method, there are only trace amounts of CBD in hemp oil or none at all.

Here are tips to consider before buying CBD products:

  1. Before making any purchase, patients should ensure first that CBD use is legal in their state.
  2. Buy high-quality items only such as non-GMO and organic, hemp-derived products.
  3. When purchasing online, make sure to check reviews and research on the brand and its offerings.
  4. Different methods are employed in extracting CBD oil. A report says that the US FDA in pharmaceutical manufacturing recommends CO2 extraction because it is recognized as a safe process (43 ) .
  5. High-quality CBD products give consumers access to batch testing reports and lab analyses. Accredited third-party laboratories issue certifications on a CBD product’s components and quality.
  6. Patients with dementia or their family members should consult with a medical professional first before buying CBD products.

CBD Dosage For Dementia

There is no standard dosage chart for CBD, as the US FDA has not approved its use other than for epilepsy. The rule is to start with small amounts and increase dosage if no adverse reactions are observed.

It is recommended to begin with a small dose of 1 to 2 mg daily for one week, then increase by 2 to 3 mg weekly until significant symptom improvements are noticed (44 ) .

The dosage should be based on the patient’s body weight—the heavier the patient, the larger their dose. For average adults, the standard dose is approximately a maximum of 5 mg.

Dementia patients or their family members should talk to a doctor before adding CBD to their medication regimen.

How to Take CBD Oil for Dementia

Several forms of CBD products are available in the market. It is recommended to administer CBD in gelcap form to dementia patients (45 ) .

Compared to tinctures (dropper), gel caps help in the administration of consistent CBD amounts. For elderly patients, the act of swallowing pills also feels more familiar.

Other product forms that will enable patients to take CBD orally include CBD oil, sprays, capsules, or gummies . If the administration of CBD to dementia patients and other diseases is complicated, CBD products can be mixed with food and beverages.

For more efficacy, tinctures may be applied sublingually (under the tongue) for 60 to 90 seconds before swallowing.

CBD oil, meanwhile, can be used during massages to relieve chronic pain in patients.

There are also topical CBD formulations available to patients, including lotions, salves, and creams. Since CBD has limited absorption when applied topically, it is recommended to purchase products that use CBD micellization, encapsulation, or nanotechnology.

The methods and technologies mentioned above guarantee that the active ingredient CBD is transmitted through dermal layers and does not merely stay on the skin.

CBD vapes and pens are also available, but these are not recommended for dementia patients who are usually elderly.


Currently, there is no absolute cure for dementia.

Symptoms of Alzheimer’s and other neurodegenerative diseases can only be managed, not cured completely. Thus, patients and their family members are turning to alternative treatments like CBD.

Several studies support the use of CBD in the treatment of dementia because of its excellent safety profile. Side effects of CBD are minimal and rarely adverse.

CBD’s benefits on neurodegenerative diseases include its anti-inflammatory and antioxidant properties. It also has neuroprotective and brain-stimulating effects that may have therapeutic benefits on dementia patients.

Further studies need to be conducted, especially on the proper dosage of CBD to achieve maximum efficacy in treating dementia.

Family members are recommended to consult with a doctor first before administering CBD to their loved ones with dementia.

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