People taking high doses of CBD may show abnormalities in liver related blood tests. Many non-prescription drugs, such as acetaminophen (Tylenol), have this same effect. So, you should let your doctor know if you are regularly using CBD.
CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.
Cannabidiol (CBD) is often covered in the media, and you may see it touted as an add-in booster to your post-workout smoothie or morning coffee. You can even buy a CBD-infused sports bra. But what exactly is CBD? And why is it so popular?
The evidence for cannabidiol health benefits
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer or COVID-19, which it is not. We need more research but CBD may prove to be a helpful, relatively non-toxic option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD currently is typically available as an unregulated supplement, it’s hard to know exactly what you are getting.
CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
How is cannabidiol different from marijuana, cannabis and hemp?
CBD comes in many forms, including oils, extracts, capsules, patches, vapes, and topical preparations for use on skin. If you’re hoping to reduce inflammation and relieve muscle and joint pain, a topical CBD-infused oil, lotion or cream – or even a bath bomb — may be the best option. Alternatively, a CBC patch or a tincture or spray designed to be placed under the tongue allows CBD to directly enter the bloodstream.
The Farm Bill removed all hemp-derived products, including CBD, from the Controlled Substances Act, which criminalizes the possession of drugs. In essence, this means that CBD is legal if it comes from hemp, but not if it comes from cannabis (marijuana) – even though it is the exact same molecule. Currently, many people obtain CBD online without a medical marijuana license, which is legal in most states.
It is important to note that while cannabidiol shows promise in the treatment of some symptoms and conditions, further research is needed. Additional studies may explore variations in dosages and administration as well as how treatment with cannabidiol compares to other medications and treatment options.
Although the subject is complex, studies have shown some neuroprotective effects of CBD. Research comparing the brains of chronic marijuana smokers and the amount of THC and CBD on hair samples indicated that, while THC appears to have a neurotoxic effect—diminishing grey matter in areas of the brain—CBD appears to have a protective effect on the same areas of the brain.
Types of Cannabidiol
There is increasing evidence that CBD may have potential therapeutic benefits, including anticonvulsive, sedative, hypnotic, antipsychotic, and neuroprotective properties. It also has an anti-inflammatory effect, which in animal studies has been found to be more potent than that of aspirin (acetylsalicylic acid).
Cannabidiol, or CBD, is an active ingredient in the drug cannabis, also known as marijuana. CBD is the second-most prevalent compound of marijuana, after delta-9-tetrahydrocannabinol, or THC. Marijuana contains over 400 different active substances, and THC and CBD are just two of its 60 different cannabinoid molecules.
Impact of Cannabidiol
While research suggests that cannabidiol is generally well tolerated, you may experience some side effects while taking CBD products. Some of these side effects can include: