Read about CBD Oil for the Thyroid Gland ✅ – Health Magazine Health, Medicine, Fitness, Nutrition, Endocrine News Thyroid disorders affect an increasing number of the global population. CBD interacts with the cannabinoid receptors located on the thyroid gland — can it help with hormonal imbalances? CBD in the treatment of thyroid gland. The influence of CBD on hormones. CBD compound with the thyroid gland,. Read more!
CBD Oil for the Thyroid Gland
CBD oil is a new product that has been shown to help with many health issues such as chronic pain and inflammation, epilepsy, depression and anxiety, nausea induced by chemotherapy, arthritis, and much more. This oil is composed of a high concentration of CBD, a chemical compound found within the Cannabis plant. CBD does not possess any psychoactive properties and therefore will not affect your state of mind after consumption. One notable quality of CBD oil that has been focused on recently is the ability to assist with thyroid disorders, as an alternative treatment option.
What is the thyroid gland?
The thyroid gland is a part of the endocrine system and it is found at the base of the neck, in front of the trachea. There are various hormones that are secreted by the thyroid gland overall it must regulate multiple body systems that facilitate heart health, muscle functioning, and strong bones.
Additionally, our metabolism, temperature (homeostasis- the body’s ability to maintain a stable environment despite external changes), and even our mood is affected by the thyroid gland. As you can probably glean, the thyroid gland is very important within the human body and disorders affecting the thyroid’s hormone production can have detrimental effects.
Since the thyroid gland produces a hormone that controls so many different processes in the body, if it’s too active (hyperthyroidism) or not active enough (hypothyroidism), it’s very problematic for vital organs. Here are a few thyroid disorders that can occur if the thyroid isn’t operating as it should:
- Thyroid cancer
- Goiter (swollen thyroid)
- Graves’ disease (overactive thyroid)
How does CBD Oil Help?
CBD oil can be very beneficial for thyroid disorders because studies have shown that it has the capacity to help regulate the endocrine system by encouraging the glands to function properly. Our bodies have cannabinoid receptors and these receptors bind with cannabinoids and they send signals to different systems within our bodies.
Neurons that control the thyroid are signaled by the cannabinoid receptors to release the proper amount of hormones. CBD also helps with inflammation within the body, including the thyroid gland because it has natural anti-inflammatory properties. Therefore not only does it assist with regulating thyroid hormone secretion, it keep swelling at bay and addresses underlying causes to thyroid disorders such as digestive issues. This is done through regulating the contractions in your intestines to stop issues such as frequent bowel movements, constipation, etc; all of which can occur due to an overactive or inactive thyroid gland.
CBD oil can also help control anxiety that occurs with thyroid disorders. The proper dosage varies from person to person and it is recommended to do thorough research and consultation when considering using CBD oil to help regulate thyroid activity.
CBD For Thyroid Health: Can It Help As Alternative Medication?
The thyroid is a critical endocrine gland that is situated at the base of the neck, wrapping around the front of the trachea. The thyroid produces a variety of hormones that influence bodily functions, such as metabolic rate, bone density, heart health, and muscle strength.
The gland connects with the brain, establishing a state of hormonal homeostasis. The thyroid regulates processes like emotional control, body temperature, heart rate, mood, metabolism, and more.
Thyroid dysfunctions can result in a range of symptoms that stem from imbalances in the above functions.
Scientists have found a link between the human endocannabinoid system (ECS) and brain/thyroid communication. The ECS is a potential therapeutic target for the management of hormones production, which suggests that using cannabinoids could improve thyroid health and effectively manage thyroid disorders.
In this article, we elaborate on the benefits of CBD oil for thyroid health; we’ll touch on the subject of hormonal imbalances, different types of thyroid disorders, and how to use CBD for the side effects of thyroid dysfunctions.
CBD and Thyroid Health: What You Need to Know
The research into CBD and thyroid health is in the early stage, but some studies suggest that CBD may be an effective therapeutic agent for the management of thyroid disorders.
Humans and all animals — except for insects — have an endocannabinoid system (ECS). The ECS is our major regulatory network that controls a variety of biological processes, including mood, memory, immune response, body temperature, appetite, fertility, sensory perception, neuroprotection, and more.
Let’s take a look at the current state of scientific knowledge when it comes to using CBD for thyroid health.
Studies on CBD and Thyroid Health
A 2015 study found significant concentrations of CB1 and CB2 cannabinoid receptors in the thyroid glands. These receptors were associated with the shrinkage of thyroid tumors, showing promise as potential blockers of the spread of malignant cells on the gland (1).
Researchers are still trying to figure out the role of CBD and cannabinoid receptors in the management of conditions like Hashimoto’s Disease or Graves’ Disease. Nevertheless, these receptors and their interaction with the thyroid gland and function sheds new light on using natural resources to take care of thyroid health.
A growing number of studies suggest that CBD and other cannabinoids can be used for dealing with the symptoms associated with thyroid conditions, including skin problems, inflammation, pain, anxiety and depression, weight gain, and low energy levels.
In a study published in the Journal of Experimental Medicine, the authors found that CBD and its modified equivalents were effective in easing chronic inflammatory and neuropathic pain in rats (2).
Scientists believe that oral forms of CBD — such as CBD oil or capsules — produce better effects from the symptoms caused by internal imbalances, especially when it comes to anxiety and depression. On the other hand, topical products are more effective for problematic areas on the body.
Effects of CBD Oil on Thyroid Disorders
The thyroid often suffers from nutrient deficiencies, lacking iodine, selenium, and zinc. Specific environmental factors, such as excessive stress, can also cause the underperformance of the land.
Another risk factor for thyroid disorders is an autoaggressive immune system. When the immune system attacks the thyroid glands, it can cause autoimmune disorders, such as Hashimoto’s Disease or Graves’ disease.
Symptoms of thyroid disorders include:
- Small lumps on the thyroid gland that may cause excess production of hormones
- Hyperthyroidism, which happens when there are too many thyroid hormones
- Hypothyroidism, which is associated with low levels of thyroid hormones
- Thyroid storm, which is a rare type of hyperthyroidism
- Swelling of the thyroid (goiter)
- Thyroid cancer
Overproduction or underproduction of the thyroid hormones may ravage a person’s health over time. Thyroid disorders are challenging to treat due to the difficulties in diagnosis. Thyroid conditions can have several underlying causes associated with physical functions.
Doctors use special tests to diagnose thyroid imbalances, including biopsies and imaging scans, such as ultrasound or iodine screenings. Patients are also asked to run a test for T3, T4, and thyroid-stimulating hormone (TSH) to search for thyroid imbalances.
The THS is a figure that measures the amount of thyroxine (T4) that the thyroid gland should release.
Below we cover the potential benefits of CBD for thyroid health.
CBD Oil for Hormonal Balance
The endocrine system is made of a number of glands in the body that produce and secrete hormones for different functions.
These hormones affect a variety of physiological processes, such as growth, movement, respiration, sensory perception, and fertility.
A 2018 study performed by the Polish Society of Endocrinology investigated potential interrelations between the ECS and the functioning of the endocrine system (3).
As mentioned, the ECS is involved in regulating a wide range of critical functions, including the performance of the thyroid.
The potential benefits of CBD for thyroid health are expressed through their interaction with the body’s ECS and its two types of receptors — CB1 and CB2.
Researchers have discovered the presence of CB1 receptors on the thyroid gland of animal models. These receptors regulate the production of two thyroid hormones, T3 and T4.
These hormones play an important role in modulating energy levels, body weight, temperature, as well as the growth of hair, nails, and skin cells.
Cannabinoid receptors have also been found within the hypothalamic paraventricular nucleus (PVN), which is a region in the brain that connects with the pituitary gland and stimulates it to produce different types of hormones to adrenal glands, gonads, and the thyroid.
CBD indirectly engages with these receptors, which would explain their potential for managing thyroid disorders, especially the problems of hormonal imbalances.
However, we still need more quality studies on humans to support preclinical findings.
CBD Oil for Anxiety
CBD has remarkable anxiolytic (anti-anxiety) properties due to its interaction with several mechanisms that control our responses to stress.
One of such mechanisms is the agonism of the 5-HT1A receptor, which controls serotonin secretion. Serotonin is a neurotransmitter that manages feelings of happiness, well-being, and relaxation (4).
Moreover, CBD changes the shape of the GABA-A receptor, which acts as a handbrake for the brain to prevent overexcitation (5). The administration of CBD causes this receptor to use the GABA neurotransmitter more effectively, keeping us calm during stressful events.
CBD can also temporarily lower blood pressure, allowing the user to take deeper breaths. This, in turn, can have a positive effect on our physical response to stress (6).
CBD Oil for Sleep
Anxiety is one of the major contributors to sleep deprivation, which is one of the reasons why people use CBD oil for sleep disorders. Aside from that, CBD influences the functioning of our circadian rhythm.
In other words, CBD regulates our sleep-wake cycle. Taking lower doses in the morning may not only reduce anxiety but also improve energy and focus, thus increasing productivity (7). With heightened daily alertness throughout the day, our body starts to receive signals that it has done enough work for the day and it’s time to go to bed. Consistent supplementation with CBD can help the body manage its melatonin levels, which is a hormone that helps the body set the right gears in motion to fall asleep faster
On the opposite side, higher doses taken in the evening may promote sedation on top of the aforementioned lowering of the blood pressure. Many people use CBD oil an hour or two before going to bed to help themselves get more restful sleep (8).
Studies have shown that CBD also helps us stay longer in the deep sleep stage while reducing REM disorders.
CBD Oil for Metabolism & Low Energy Levels
As mentioned, low doses of CBD taken throughout the day can stimulate our energy levels, which is a common problem among people with thyroid disorders. Another issue with compromised thyroid health is disrupted metabolism, which results in weight gain and feelings of tiredness.
CBD is known to regulate metabolism through its interaction with the ECS. One positive effect worth mentioning is CBD’s ability to promote the fat browning effect.
Fat browning refers to the conversion of white fat cells to brown fat cells (9). The brown cells are more effective when it comes to converting fat to energy, helping individuals burn more calories as a result. On top of that, cannabinoids may have a positive effect on metabolism through improving the body’s sensitivity to insulin and reducing blood sugar levels as a result.
A 2013 review of the existing studies on cannabis and metabolism showed that regular cannabis users have lower fasting insulin resistance, lower blood sugar levels, and smaller waist circumference. However, the review looked into the efficacy of cannabinoids on metabolism in general, not CBD alone (10).
CBD Oil for Pain
Problems with thyroid health often involve episodes of pain, especially in the joints and muscles. CBD has been shown to mitigate pain signaling through the indirect interaction with opioid and vanilloid receptors in the brain, which modulate pain perception (11). CBD also has strong anti-inflammatory properties, which could potentially help reach the underlying cause of pain (12).
Does CBD Oil Help with Inflammation in Thyroid?
A high-quality CBD oil may address a variety of thyroid dysfunctions. This underperformance includes hypothyroidism, hyperthyroidism, goiter, thyroiditis, and thyroid storm.
All of the above conditions are triggered by chronic inflammation of the thyroid gland due to the body’s autoaggressive actions on this organ.
CBD is a powerful anti-inflammatory compound. Multiple studies have proven the role of cannabinoids in reducing organ and tissue inflammation.
Although research on the efficacy of thyroid disorders is in its infancy, current studies regarding CBD’s influence on hormonal activity is promising.
However, the amount of research is insufficient to define CBD as an effective treatment for thyroid health problems; we need more clinical trials to come to this conclusion.
CBD and Thyroid Medication Interactions
The topic of CBD-drug interactions is a complex one. CBD is known to inhibit the activity of the Cytochrome p450 system, a set of enzymes responsible for metabolizing the active ingredients in medications. This applies to both prescription and OTC meds.
When you take CBD along with thyroid medication, the aforementioned interaction may result in either subtherapeutic effects or toxic levels of the drugs in the bloodstream.
In the first scenario, your primary medicine may lose efficacy and thus fail to provide the desired effects.
The second scenario is more negative because it entails the risk of experiencing the second-hand side effects that don’t result from CBD alone but rather from the above interaction.
If you want to avoid CBD-drug interactions, we encourage you to consult a doctor before buying a CBD product for thyroid health.
Does CBD Oil Interact with Levothyroxine?
Having read about potential CBD-drug interactions might have you wonder whether you should totally ditch CBD when taking thyroid medications, such as levothyroxine.
Levothyroxine is the most popular thyroid medication. Like many other pharmaceuticals, it is processed by the same group of enzymes as CBD.
In simple words, when you take CBD oil with levothyroxine at one time, they will likely compete for the place in the liver. Therefore, using these two products together may be counterproductive.
We have looked into many forums for patients with thyroid disorders who also take CBD for their conditions. The vast majority reports little to no side effects, but they underline the importance of having a 2-hour gap between one compound and the other.
Again, the only person qualified to rule out any recommendations in this subject is an endocrinologist, preferably one with sufficient knowledge about cannabis. No two individuals are the same, so what works for you (or is safe for you) won’t necessarily provide the same results for another person.
Final Thoughts on CBD and Thyroid Health
Due to its interaction with the endocannabinoid system (ECS), CBD allows individuals to take on an alternative route to managing the level of thyroid hormones in the blood. This, in turn, holds promise for patients with thyroid disorders who are apprehensive about conventional methods.
Most hypothyroidism or hyperthyroidism cases can be dealt with a properly adjusted dose of thyroid hormone. Healthy nutrition and an active lifestyle can also contribute to the mitigation of symptoms.
CBD oil can support thyroid treatment by helping the body regulate its critical functions. However, CBD for thyroid conditions is a subject that still requires more research.
Those interested in trying CBD should seek medical advice from a doctor. Making changes to one’s health care routine without the supervision of a qualified physician can do more harm than good. Doctors also have to be notified if a person is already taking thyroid medications or any other prescription meds that could potentially interact with CBD.
- Lakiotaki, Eleftheria et al. “Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions.” BioMed research international vol. 2015 (2015): 839403. doi:10.1155/2015/839403
- Xiong, Wei et al. “Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.” The Journal of experimental medicine vol. 209,6 (2012): 1121-34. doi:10.1084/jem.20120242
- Borowska, Magdalena et al. “The effects of cannabinoids on the endocrine system.” Endokrynologia Polska vol. 69,6 (2018): 705-719. doi:10.5603/EP.a2018.0072
- Russo, Ethan B et al. “Agonistic properties of cannabidiol at 5-HT1a receptors.” Neurochemical research vol. 30,8 (2005): 1037-43. doi:10.1007/s11064-005-6978-1
- Pretzsch, Charlotte Marie et al. “Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder.” Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol. 44,8 (2019): 1398-1405. doi:10.1038/s41386-019-0333-8
- Jadoon, Khalid A et al. “A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study.” JCI insight vol. 2,12 e93760. 15 Jun. 2017, doi:10.1172/jci.insight.93760
- Murillo-Rodríguez, Eric et al. “Potential effects of cannabidiol as a wake-promoting agent.” Current neuropharmacology vol. 12,3 (2014): 269-72. doi:10.2174/1570159X11666131204235805
- Babson, Kimberly A et al. “Cannabis, Cannabinoids, and Sleep: a Review of Literature.” Current psychiatry reports vol. 19,4 (2017): 23. doi:10.1007/s11920-017-0775-9
- Parray, Hilal Ahmad, and Jong Won Yun. “Cannabidiol promotes browning in 3T3-L1 adipocytes.” Molecular and cellular biochemistry vol. 416,1-2 (2016): 131-9. doi:10.1007/s11010-016-2702-5
- Penner, Elizabeth A et al. “The impact of marijuana use on glucose, insulin, and insulin resistance among US adults.” The American journal of medicine vol. 126,7 (2013): 583-9. doi:10.1016/j.amjmed.2013.03.002
- Russo, Ethan B. “Cannabinoids in the management of difficult to treat pain.” Therapeutics and clinical risk management vol. 4,1 (2008): 245-59. doi:10.2147/tcrm.s1928
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Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
CBD in the treatment of thyroid gland
CBD is one of the major cannabis plant compounds. In the past few years, there has been a huge increase in interest in CBD supplementation. As a result of increasing popularity, scientists pay more and more attention in their research to capturing the various benefits and properties that comes with the use of CBD oils. So, thanks to their versatility and wide spectrum of activity, CBD oils and other cannabinoids through hormonal stimulation, can directly influence hormone levels and their work?
Table of Contents
CBD in the treatment of thyroid gland. Thyroid hormone – basic knowledge
To understand the impact of CBD on the endocrine system it is necessary to get acquainted with the basic knowledge compendium on hormones, the endocrine system and their interrelationship. Hormones are chemical messengers produced by the human body, responsible for the coordination and regulation of the most important processes taking place in the body, including:
- sexual functions,
- mood and well-being.
The hormonal system (endocrin) consists of various glands that produce hormones such as thyroid, pituitary gland, pancreas, pineal glands, etc. Hormones produced by these glands are particularly strong chemical substances that significantly affect the body, because The endocrine system is an important adaptation mechanism to the changing conditions of the external and internal environment.
The influence of CBD on hormones. CBD compound with the thyroid gland
Researchers have repeatedly demonstrated that the endocannabinoid system is also involved in the regulation of endocrine processes that directly affect the activity of the endocrine glands mentioned above (including thyroid gland). Therefore, appropriate stimulation of the endocannabinoid system using CBD has a direct effect on the hormonal level of the human body.
CBD in the treatment of thyroid gland. Hyperthyroidism
Hyperthyroidism – otherwise overproduction of thyroid hormones.
Graves’ disease – a type of hyperthyroidism caused by excessive activity of the entire thyroid gland. The cause of Graves’ disease is abnormal functioning of the body’s immune system, which is responsible for fighting all diseases. The main symptoms of the disease include:
- anxiety and irritability,
- slight trembling of hands and fingers,
- hypersensitivity to elevated temperature in the environment,
- excessive sweating,
- sleep disorders,
- diarrhea (despite a constant, constant diet and eating habits),
- thyroid enlargement (so-called goiter),
- disorders of menstrual cycles,
- erectile dysfunction (men),
- decreased libido (women),
- protruding eyes (stare out),
- irregular, accelerated heartbeat,
- thick, red skin (around the tibia).
In the case of many patients struggling with overactive thyroid using cannabidiol, the relief of many negative symptoms of this disease has been noticed. Regular use of CBD oils allows you to return to normal body weight by stopping the existing diarrhea and restoring the patient’s appetite. CBD also eliminates persistent sleep disorders related to anxiety, irritability and anxiety that accompany Graves’ disease. In addition, the CBD regulates the heart, the trembling of hands and fingers, as well as any muscular pains occurring with varying frequency and intensity in the patient.
CBD in the treatment of thyroid gland. Hypothyroidism
Hypothyroidism – one of the most common diseases with hypothyroidism is:
Hashimoto – an autoimmune disease in which the body attacks thyroid cells, causing chronic thyroiditis as a result of stopping the production of its hormones. It is a very difficult disease to detect, most often occurring in mature women, however, often found in men, and even in young children. It is an autoimmune disease that arises as a result of the immune system’s mistake, in the consequence of which the body turns itself against itself, destroying thyroid proteins, recognizing them as hostile. The most common symptoms of Hashimoto:
- problems with concentration and concentration of attention,
- depressive states,
- skin problems (dry skin),
- aching muscles and joints,
- weight gain,
- hair loss,
- elevated cholesterol.
Due to its immunomodulatory properties and ingredients, CBD can bring positive reactions of the body not only in terms of alleviating the symptoms of thyroiditis, but also by acting directly on the destructive inflammatory process. Effective action of cannabidiol is confirmed in such autoimmune diseases as for example: multiple sclerosis or Crohn’s disease. To date, these assumptions have not been scientifically confirmed, but the whole allows us to look at the possible inhibition of thyroid cell destruction due to the positive properties and action of cannabidiol. Patients struggling with hypothyroidism also notice alleviation or even complete elimination of nagging headaches, muscles and joints. CBD allows restoring patients to a restful sleep, increase concentration, eliminating arduous tension and depression.
Thyroid nodular goiter is a condition where one or more nodules are located in the thyroid structure. The resulting nodules give off the wrong amount of hormones, disturbing the chemical balance of the human body. The use of CBD may have a significant impact on improving the patient’s health in this disease. There is a high probability that cannabinoids reduce nodules formed on the thyroid.
De Quervain’s disease – (subacute inflammation of the thyroid gland), although the etiology of the disease is not completely clear and known, its causes are sought in a viral infection. The most common symptoms of the de Quervain syndrome are:
- neck pain,
- thyroid function disorders.
CBD has strong anti-inflammatory properties, so it can be a reliable way to get rid of dangerous thyroid inflammation.
Thyroid cancer – affects a small percentage of the population (about 5%). Every year, researchers and researchers provide ever newer, more reliable information confirming the anti-cancer effect of cannabidiol. Although the mere introduction of CBD to the treatment process of the disease, it does not guarantee a complete disposal of its effects, for many patients is a source of elimination of nagging symptoms.
In particular, cannabidiol helps to eliminate or greatly alleviate such symptoms of the disease as:
- tiredness, powerlessness,
- pains of various origins (muscles, joints, head, migraines),
- depressive states, irritability, fears, anxiety (more on the subject in the article – CBD and anxiety)
In addition, CBD, thanks to its properties, allows patients to reduce analgesics and sleeping pills, protecting the body against the possible risk of addiction to painkillers or hypnotics. A properly adjusted dose of the drug in the form of thyroid hormones (in the case of hypothyroidism) or blocking their production (in overactivity), appropriate diet and lifestyle in combination with CBD supplementation guarantees patients proper functioning. The best CBD products can be found here.