cbd syndrome

Tau occurs naturally in the brain and is usually broken down before it reaches high levels. In people with CBD, it isn’t broken down properly and forms harmful clumps in brain cells.

If you have CBD, your clinical team will pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS).

Diagnosing CBD

The surface of the brain (cortex) is affected, as well as a deep part of the brain called the basal ganglia.

CBD occurs when brain cells in certain parts of the brain are damaged as a result of a build-up of a protein called tau.

Outlook

CBD is caused by increasing numbers of brain cells becoming damaged or dying over time.

It’s also common for someone with CBD to experience personality changes, such as becoming apathetic, irritable, agitated or anxious.

Walking, balance and co-ordination may get worse. Many people have problems with their speech, which will become slow and slurred.

Some people also develop problems with walking and co-ordination.

As CBD reaches an advanced stage, muscle stiffness will continue to get worse. People with the condition may lose the ability to move 1 or more limbs. Some people are unable to walk and need a wheelchair or assistance to transfer (such as help getting into and out of bed).

Mid-stage symptoms

Some of the main symptoms of CBD are outlined below. Most people with the condition won’t experience all of these.

As CBD progresses, it may eventually start to cause problems in your other limbs.

The symptoms typically become more severe over several years, although the speed at which they worsen varies.

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Early symptoms

Other problems people with advanced CBD can experience include:

CBD typically affects one of the limbs at first. This is usually a hand or arm, but sometimes a leg.