olej cbd chicago

CBD is a compound derived from the cannabis plant. Cannabis is the source of one of the oldest plant-based medicines known to man, and for thousands of years it has been cultivated by humans for various purposes. 2 Two common strains of the plant are marijuana, cultivated for its medicinal purposes, and hemp, cultivated for its use in food, clothing, and paper. 3 The cannabis plant contains various active components, two of which are cannabinoids and terpenes. 2 Researchers have identified up to 113 different cannabinoids and 120 different terpenes in cannabis. 4 The two cannabinoids delta-9-tetrahydrocannabinol (THC) and CBD are the most prevalent and well-known cannabis components. However, terpenes have also been shown to bind to receptors in animal studies, suggesting that they may play a role in the overall pharmacologic profile of cannabis. 2 Many people likely associate cannabis with marijuana and the “high” effect that it elicits. This psychoactive effect is a result of the action of THC on cannabidiol (CB)1 and CB2 receptors. 5 CBD does not act in the same way; in fact, it is thought to have antagonistic effects on the CB receptors. As a result, it does not produce the psychoactive effects seen in THC-containing cannabis. 5 CBD has a long list of proposed benefits, including potential antiepileptic, anxiolytic, antipsychotic, anti-inflammatory, and neuroprotective effects. 6 Medicinal marijuana products often contain a combination of THC and CBD but may also be pure THC or CBD alone. CBD oil, however, primarily contains the CBD, with minimal (<0.3%) THC content.

Cannabidiol (CBD) oil is a supplement that has gained tremendous popularity over the past few years. The compound is marketed for numerous indications and sold across the United States by various shops, gas stations, and online retailers. CBD is produced in a variety of formulations, one of the more prevalent being CBD oil. 1 One area in which CBD oil is gaining interest is the cancer setting, and because of its wide availability, it is likely that many cancer patients are turning to this alternative medicine to help manage their disease or symptoms. It is therefore important for healthcare professionals to educate themselves regarding the efficacy, safety, and legality of this compound.

Cannabinoids have been used to treat patients with cancer since 1985, when dronabinol (Marinol), a synthetic THC product, was approved by the FDA to treat chemotherapy-induced nausea and vomiting. 17 The specific role of CBD in cancer treatment is still unclear. In vitro and in vivo studies have shown some evidence for CBD’s efficacy as an anticancer agent through mechanisms such as induction of apoptosis or inhibition of tumor growth and metastasis. 18,19 In vitro data supports the ability of CBD to induce tumor cell death in patients with glioblastoma. 20 Furthermore, case reports have been published showing a potential anticancer effect in lung cancer and ovarian cancer patients. 21,22 Regarding supportive care for cancer patients, the role of CBD is again unclear. Evidence exists for the use of cannabis for chemotherapy-induced nausea and vomiting, cancer pain, anorexia and cachexia, and appetite stimulation; however, most studies were poorly designed and evaluated products that also contained THC. 2 Until more human trial data become available, the appropriateness of using CBD oil in these indications remains uncertain. Several studies are investigating the use of CBD in patients with cancer for indications such as palliative care in cancer patients to reduce symptom burden; as standard-of-care treatments in patients with multiple myeloma, glioblastoma multiforme, and gastrointestinal malignancies; and for prevention of graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation. 23-25 Continuing research is necessary to understand CBD’s usefulness in treating cancer patients.

Olej cbd chicago

THC’s Entourage

Adriaen Block, Queens, NY

Everyday there are new uses for CBD oil being discovered, tested, talked about. Intriguing studies about how it may help with various dementias including Alzheimers are exciting. Another booming area is relief for Erectile Dysfunction.

Can CBD Replace Ibuprofen?

It is this considerable difference in the risk profile of CBD versus Ibuprofen that makes CBD an exciting alternative. With more research, CBD may prove more beneficial for certain types of long-term and difficult to treat pain and inflammation. Also, because CBD has a low chance of severe side effects when used daily, many people are already using it to replace over the counter NSAIDS. Of course, the research is still playing catch up with the many real-world patient experience and anecdotal reports.