Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil, Irmandade da Santa Casa de Misericórdia de Porto Alegre (ISCMPA), Porto Alegre, RS, Brazil
All of these studies showed interesting results, but sample sizes were very small and the duration of follow-up was very short. The Movement Disorder Society Evidence-Based Medicine Committee recommendations for treatments of PD published in 2018 concluded that there was insufficient evidence to support the use of CBD for the treatment of PD at the time.5
There is a clear need for therapies that target other pharmacological systems. A multimodal approach combining activity on dopaminergic as well as non-dopaminergic system would be very helpful and needs to be explored.
Cannabis also could interact with other medications you are taking. While interactions are largely unknown, adding cannabis to a complex regimen of Parkinson’s and other prescription medications could present a risk. It’s important to tell your Parkinson’s doctor what you are taking, so that they can alert you to possible interactions.
Try to be open, honest and willing to hear what your doctor says. Tell them you are looking at all treatment options and want to learn if and how cannabis might help. And if you are considering or taking specific products, share which. (Bring printed information or a picture of the label.)
Under federal law, doctors cannot prescribe cannabis. But qualified doctors (those who have completed additional training and registration) can issue “certifications” that permit patients to get a license for medical cannabis. Many doctors choose not to pursue qualification and therefore are not able to issue certifications. (Some states maintain registries of qualified doctors that you can search online.)
Marijuana comes from the Cannabis plant, which contains hundreds of different components, including cannabinoids. Cannabinoids bind to receptors throughout the brain and body to influence movement, mood, inflammation and other activities. Many of these receptors are in areas of the brain impacted by Parkinson’s disease (the basal ganglia).
How can I access cannabis?